ClearLight Closes Lab Services and Offers Expert Consulting Services Learn More

CLARITY for mapping the nervous system

Posted on Feb 03, 2013

With potential relevance for brain-mapping work, hydrogel-based structures can now be built from within biological tissue to allow subsequent removal of lipids without mechanical disassembly of the tissue. this process creates a tissue-hydrogel hybrid that is physically stable, that preserves fine structure, proteins and nucleic acids, and that is permeable to both visible-spectrum photons and exogenous macromolecules. here we highlight relevant challenges and opportunities of this approach, especially with regard to integration with complementary methodologies for brain- mapping studies.

By Kwanghun Chung & Karl Deisseroth

Nature Methods 2013 VOL.10 NO.6

Download the Full Paper to Read More




Analysis can be performed for select biomarkers, please contact us to find out if your target of interest is one of them. Imaging is currently performed on select fields of view instead of the entire sample.

Submission Guidelines

Tissue Sample Requirements: