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Learning Center

All About Tissue Clearing and IHC

Gain a better understanding of the tissue microenvironment


Learning Center Resources

Welcome to the ClearLight Bio learning center. Here you can gain a refresher on CLARITY Tissue Clearing and 3D Immunohistochemistry or take your learning to the next level. Study the differences among popular tissue clearing protocols by visiting the Tissue Clearing Comparison. Visit Applications to view CLARITY and 3D IHC techniques applied to tissues ranging from brain to bone.

More Details When Needed

Watch videos that showcase various research projects and that explain in greater detail the various steps in the tissue processing workflow. Visit the resources page to find downloads, case studies, publications, and links to external resources.  If you need help or have a suggestion for the ClearLight Bio learning center please contact us.

CLARITY Tissue Clearing Step-by-Step

Visit the CLARITY tissue clearing page to learn about CLARITY and the tissue processing workflow.

3D Multiplex Immunohistochemistry

Gain a historical perspective of immunohistochemistry as well as modern possibilities with 3D IHC

Tissue Clearing Applications - From Brain to Bone

See tissue clearing applications for normal and diseased tissues of varying lipidity and complexity.

Tissue Clearing Comparison

See a head-to-head comparison of popular tissue clearing protocols .

Z-Stack and 3D IHC Videos

Visit the video gallery to view CLARITY IHC Multiplexing and See More Biology.


Find downloads, case studies, publications, and links to external resources.


Try CLARITY Tissue Clearing in Your  Lab

CLARITY Tissue Clearing Kit – Low Lipid

CLARITY Tissue Clearing Kit – High Lipid

Analysis can be performed for select biomarkers, please contact us to find out if your target of interest is one of them. Imaging is currently performed on select fields of view instead of the entire sample.

Submission Guidelines

Tissue Sample Requirements: