Tissue Clearing Applications


CLARITY Tissue Clearing

ClearLight has applied CLARITY to a range of organoids. This area holds much promise for understanding drug responses and disease models.

Tissue Clearing Organoids Combined with 3D IHC

Organoids have gained a lot of popularity in recent years - especially for use in drug development and research. These 3D cell cultures that can represent most of the major organs of the body and their cellular orientation and relationships more closely resemble those of actual tissue. Organoids can produce stunning imagery, especially when their three dimensional advantages are retained through CLARITY Tissue Clearing and 3D IHC.


These are human iPSC-derived cortical brain organoids.

 Collaborative Research Organization for Tissue Clearing Tonsil and Tru3D Tissue Analysis

Leverage our Internal R & D

When you work with us you gain the benefit of our internal experiments, assessments, and rigorous testing. In addition to performing our lab services: CLARITY Tissue Clearing, 3D IHC, and Tru3D Tissue Analysis, ClearLight scientists perform internal Research and Development to advance our understanding and applications of CLARITY to other tissue types and downstream applications. Researchers who work with us benefit from this exploratory work. The ClearLight “lab basement” is full of failed or pivoted experiments that helped inform our path to arrive at what does work. Work with us to avoid making the same mistakes that we have made or going down the blind alleys that we’ve pivoted away from.

“If you don’t want to spend the time figuring it out, we can help. We work hard to make this look easy.” - Dr. Sharla White, VP of Research and Development

Ready to Discuss Your Research Question? Meet with our Application Scientist.

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Analysis can be performed for select biomarkers, please contact us to find out if your target of interest is one of them. Imaging is currently performed on select fields of view instead of the entire sample.

Submission Guidelines

Tissue Sample Requirements: