Tissue Clearing Applications

Kidney Tissue

Tissue Clearing Kidney

By clearing sectioned or whole mouse kidneys coupled with 3D imaging, researchers can gain new insights into kidney structure and function.

Mouse Kidney Evaluated Using CLARITY Tissue Clearing and 3D IHC

A normal mouse kidney was evaluated using ClearLight’s CLARITY technology. DAPI clearly identified the individual cell nuclei present within the tissue. Both alpha smooth muscle actin (α-SMA) shown in red and CD31 shown in green were used to observe possible vasculature with some signal co-localization observed in certain vessels.

 Collaborative Research Organization for Tissue Clearing Tonsil and Tru3D Tissue Analysis

Leverage our Internal R & D

When you work with us you gain the benefit of our internal experiments, assessments, and rigorous testing. In addition to performing our lab services: CLARITY Tissue Clearing, 3D IHC, and Tru3D Tissue Analysis, ClearLight scientists perform internal Research and Development to advance our understanding and applications of CLARITY to other tissue types and downstream applications. Researchers who work with us benefit from this exploratory work. The ClearLight “lab basement” is full of failed or pivoted experiments that helped inform our path to arrive at what does work. Work with us to avoid making the same mistakes that we have made or going down the blind alleys that we’ve pivoted away from.

“If you don’t want to spend the time figuring it out, we can help. We work hard to make this look easy.” - Dr. Sharla White, VP of Research and Development

Ready to Discuss Your Research Question? Meet with our Application Scientist.

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Analysis can be performed for select biomarkers, please contact us to find out if your target of interest is one of them. Imaging is currently performed on select fields of view instead of the entire sample.

Submission Guidelines

Tissue Sample Requirements: