Tissue Clearing Applications

Clearing Eyes

Tissue Clearing Eyes

ClearLight continues to optimize and refine the clearing and staining of eyes while also retaining their shape and internal structures for 3-dimensional analysis. Retinal researchers would be interested to know that ClearLight has been working with rat and mouse eyes.

Tissue Clearing and Imaging Eyes is Challenging

Eyes are particularly challenging tissues to work with, based on their composition and fragility. It is important to not puncture the eye during acquisition. Usually, researchers have a specific region of interest in mind, not the entire eye. That said, ClearLight works to keep the entire eye intact and whole, removing the need to section or cut structures for imaging. Working with eyes requires a modified process to maintain the integrity of the “inflated” eye while seeing clearly defined areas that are distinctly different from each other.

 Collaborative Research Organization for Tissue Clearing Tonsil and Tru3D Tissue Analysis

Leverage our Internal R & D

When you work with us you gain the benefit of our internal experiments, assessments, and rigorous testing. In addition to performing our lab services: CLARITY Tissue Clearing, 3D IHC, and Tru3D Tissue Analysis, ClearLight scientists perform internal Research and Development to advance our understanding and applications of CLARITY to other tissue types and downstream applications. Researchers who work with us benefit from this exploratory work. The ClearLight “lab basement” is full of failed or pivoted experiments that helped inform our path to arrive at what does work. Work with us to avoid making the same mistakes that we have made or going down the blind alleys that we’ve pivoted away from.

“If you don’t want to spend the time figuring it out, we can help. We work hard to make this look easy.” - Dr. Sharla White, VP of Research and Development

Ready to Discuss Your Research Question? Meet with our Application Scientist.

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Analysis can be performed for select biomarkers, please contact us to find out if your target of interest is one of them. Imaging is currently performed on select fields of view instead of the entire sample.

Submission Guidelines

Tissue Sample Requirements: